Dilp8 requires the neuronal relaxin receptor Lgr3 to couple growth to developmental timing

How different organs in the body sense growth perturbations in distant tissues to coordinate their size during development is poorly understood. Here we mutate an invertebrate orphan relaxin receptor gene, the Drosophila Leucine-rich repeat-containing G protein-coupled receptor 3 (Lgr3), and find bo...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Garelli, Andres, Heredia, Fabiana, Casimiro, Andreia P., Macedo, Andre, Nunes, Catarina, Garcez, Marcia, Dias, Angela R. Mantas, Volonte, Yanel A., Uhlmann, Thomas, Caparros, Esther, Koyama, Takashi, Gontijo, Alisson M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640092/
https://ncbi.nlm.nih.gov/pubmed/26510564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9732
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