High salt reduces the activation of IL-4– and IL-13–stimulated macrophages

A high intake of dietary salt (NaCl) has been implicated in the development of hypertension, chronic inflammation, and autoimmune diseases. We have recently shown that salt has a proinflammatory effect and boosts the activation of Th17 cells and the activation of classical, LPS-induced macrophages (...

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Pubblicato in:J Clin Invest
Autori principali: Binger, Katrina J., Gebhardt, Matthias, Heinig, Matthias, Rintisch, Carola, Schroeder, Agnes, Neuhofer, Wolfgang, Hilgers, Karl, Manzel, Arndt, Schwartz, Christian, Kleinewietfeld, Markus, Voelkl, Jakob, Schatz, Valentin, Linker, Ralf A., Lang, Florian, Voehringer, David, Wright, Mark D., Hubner, Norbert, Dechend, Ralf, Jantsch, Jonathan, Titze, Jens, Müller, Dominik N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639967/
https://ncbi.nlm.nih.gov/pubmed/26485286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80919
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