High salt reduces the activation of IL-4– and IL-13–stimulated macrophages

A high intake of dietary salt (NaCl) has been implicated in the development of hypertension, chronic inflammation, and autoimmune diseases. We have recently shown that salt has a proinflammatory effect and boosts the activation of Th17 cells and the activation of classical, LPS-induced macrophages (...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Binger, Katrina J., Gebhardt, Matthias, Heinig, Matthias, Rintisch, Carola, Schroeder, Agnes, Neuhofer, Wolfgang, Hilgers, Karl, Manzel, Arndt, Schwartz, Christian, Kleinewietfeld, Markus, Voelkl, Jakob, Schatz, Valentin, Linker, Ralf A., Lang, Florian, Voehringer, David, Wright, Mark D., Hubner, Norbert, Dechend, Ralf, Jantsch, Jonathan, Titze, Jens, Müller, Dominik N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639967/
https://ncbi.nlm.nih.gov/pubmed/26485286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80919
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