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EAG2 potassium channel with evolutionarily conserved function as a brain tumor target

Over 20% of the drugs for treating human diseases target ion channels, however, no cancer drug approved by the U.S. Food and Drug Administration (FDA) is intended to target an ion channel. Here, we demonstrate the evolutionarily conserved function of EAG2 potassium channel in promoting brain tumor g...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Huang, Xi, He, Ye, Dubuc, Adrian M., Hashizume, Rintaro, Zhang, Wei, Reimand, Jüri, Yang, Huanghe, Wang, Tongfei A., Stehbens, Samantha J., Younger, Susan, Barshow, Suzanne, Zhu, Sijun, Cooper, Michael K., Peacock, John, Ramaswamy, Vijay, Garzia, Livia, Wu, Xiaochong, Remke, Marc, Forester, Craig M., Kim, Charles C., Weiss, William A., James, C. David, Shuman, Marc A., Bader, Gary D., Mueller, Sabine, Taylor, Michael D., Jan, Yuh Nung, Jan, Lily Yeh
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639927/
https://ncbi.nlm.nih.gov/pubmed/26258683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4088
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