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APOE-ε4 selectively modulates posteromedial cortex activity during scene perception and short-term memory in young healthy adults

Apolipoprotein E (APOE) ε4 is a major genetic risk factor for Alzheimer’s disease (AD), yet the mechanisms by which APOE-ε4 influences early-life brain function, and hence, in turn, risk for later-life AD, are poorly understood. Here, we report a novel, and selective, pattern of functional brain act...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shine, J. P., Hodgetts, C. J., Postans, M., Lawrence, A. D., Graham, K. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639783/
https://ncbi.nlm.nih.gov/pubmed/26552581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16322
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