Uric acid enhances the antitumor immunity of dendritic cell-based vaccine

Uric acid (UA) released from dying cells has been recognized by the immune system as a danger signal. In response to UA, dendritic cells (DC) in the immune system mature and enhance the T cell response to foreign antigens. It is conceivable that the antitumor immunity of a tumor vaccine could be pro...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Wang, Yihan, Ma, Xuelei, Su, Chao, Peng, Bin, Du, Jing, Jia, Hongyuan, Luo, Min, Fang, Chunju, Wei, Yuquan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639747/
https://ncbi.nlm.nih.gov/pubmed/26553557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16427
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