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Force Generation by Molecular-Motor-Powered Microtubule Bundles; Implications for Neuronal Polarization and Growth

The heavily cross-linked microtubule (MT) bundles found in neuronal processes play a central role in the initiation, growth and maturation of axons and dendrites; however, a quantitative understanding of their mechanical function is still lacking. We here developed computer simulations to investigat...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Jakobs, Maximilian, Franze, Kristian, Zemel, Assaf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639704/
https://ncbi.nlm.nih.gov/pubmed/26617489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00441
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