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Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
Two decades of studies in multiple model organisms have established the Hippo pathway as a key regulator of organ size and tissue homeostasis. By inhibiting YAP and TAZ transcription co-activators, the Hippo pathway regulates cell proliferation, apoptosis, and stemness in response to a wide range of...
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| Publicado en: | Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4638384/ https://ncbi.nlm.nih.gov/pubmed/26544935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.044 |
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