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Personalized treatment options for ALK-positive metastatic non-small-cell lung cancer: potential role for Ceritinib
The fusion of echinoderm microtubule-associated protein-like 4 with the anaplastic lymphoma kinase (EML4-ALK) is found in 3%–7% of non-small-cell lung cancer (NSCLC) cases and confers sensitivity to crizotinib, the first United States Food and Drug Administration (FDA)-approved ALK inhibitor drug. A...
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| Publicado en: | Pharmgenomics Pers Med |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Dove Medical Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4638315/ https://ncbi.nlm.nih.gov/pubmed/26622190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S71100 |
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