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Personalized treatment options for ALK-positive metastatic non-small-cell lung cancer: potential role for Ceritinib

The fusion of echinoderm microtubule-associated protein-like 4 with the anaplastic lymphoma kinase (EML4-ALK) is found in 3%–7% of non-small-cell lung cancer (NSCLC) cases and confers sensitivity to crizotinib, the first United States Food and Drug Administration (FDA)-approved ALK inhibitor drug. A...

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Vydáno v:Pharmgenomics Pers Med
Hlavní autoři: El-Osta, Hazem, Shackelford, Rodney
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638315/
https://ncbi.nlm.nih.gov/pubmed/26622190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S71100
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