A Membrane-Type-1 Matrix Metalloproteinase (MT1-MMP) – Discoidin Domain Receptor 1 Axis Regulates Collagen-Induced Apoptosis in Breast Cancer Cells

During tumour dissemination, invading breast carcinoma cells become confronted with a reactive stroma, a type I collagen-rich environment endowed with anti-proliferative and pro-apoptotic properties. To develop metastatic capabilities, tumour cells must acquire the capacity to cope with this novel m...

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發表在:PLoS One
Main Authors: Assent, Delphine, Bourgot, Isabelle, Hennuy, Benoît, Geurts, Pierre, Noël, Agnès, Foidart, Jean-Michel, Maquoi, Erik
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638154/
https://ncbi.nlm.nih.gov/pubmed/25774665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116006
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