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Steel factor influences the distribution and activity of murine hematopoietic stem cells in vivo.

To determine the effects of steel factor (SIF) on the number and distribution of phenotypically defined hematopoietic stem cells in vivo, mice were treated with continuous s.c. infusions of SIF for up to 7 days. The bone marrow demonstrated a transient 5-fold increase in the number of c-kit-positive...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Fleming, W H, Alpern, E J, Uchida, N, Ikuta, K, Weissman, I L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46381/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7682717/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.8.3760
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