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A novel fully-humanised 3D skin equivalent to model early melanoma invasion

Metastatic melanoma remains incurable, emphasising the acute need for improved research models to investigate the underlying biological mechanisms mediating tumour invasion and metastasis, and to develop more effective targeted therapies to improve clinical outcome. Available animal models of melano...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Hill, David S, Robinson, Neil D P, Caley, Matthew P, Chen, Mei, O’Toole, Edel A, Armstrong, Jane L, Przyborski, Stefan, Lovat, Penny E
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637991/
https://ncbi.nlm.nih.gov/pubmed/26330548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0394
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