Excess salt exacerbates blood-brain barrier disruption via a p38/MAPK/SGK1-dependent pathway in permanent cerebral ischemia

High salt diet (HSD) is one of the most important risk factors that contribute to many vascular diseases including ischemic stroke. One proposed mechanism underlying the disruption of blood-brain barrier (BBB) mediated by HSD is indirectly through enhancing blood pressure. The direct role of HSD on...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Tongshuai, Fang, Shaohong, Wan, Cong, Kong, Qingfei, Wang, Guangyou, Wang, Shuangshuang, Zhang, Haoqiang, Zou, Haifeng, Sun, Bo, Sun, Wei, Zhang, Yao, Mu, Lili, Wang, Jinghua, Wang, Jing, Zhang, Haiyu, Wang, Dandan, Li, Hulun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637879/
https://ncbi.nlm.nih.gov/pubmed/26549644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16548
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