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Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly

Acromegaly is a disorder resulting from excessive production of growth hormone (GH) and consequent increase of insulin-like growth factor 1 (IGF-I), most frequently caused by pituitary adenomas. Elevated GH and IGF-I levels results in wide range of somatic, cardiovascular, endocrine, metabolic, and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Martín-Rodríguez, Juan F., Muñoz-Bravo, Jose L., Ibañez-Costa, Alejandro, Fernandez-Maza, Laura, Balcerzyk, Marcin, Leal-Campanario, Rocío, Luque, Raúl M., Castaño, Justo P., Venegas-Moreno, Eva, Soto-Moreno, Alfonso, Leal-Cerro, Alfonso, Cano, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637865/
https://ncbi.nlm.nih.gov/pubmed/26549306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16298
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