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A De novo PAX8 mutation in a Chinese child with congenital thyroid dysgenesis

Background: Thyroid dysgenesis (TD) is the most frequent cause of congenital hypothyroidism (CH), but its pathogenesis remains unclear. As a thyroid transcription factor, paired box transcription factor 8 (PAX8) is essential for thyroid organogenesis and development. Aim: To screen PAX8 mutations an...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Zou, Hui, Chai, Jian, Liu, Shiguo, Zang, Hongwei, Yu, Xiaoxia, Tian, Liping, Li, Huichao, Han, Bingjuan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637687/
https://ncbi.nlm.nih.gov/pubmed/26617871
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