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Decitabine induces G2/M cell cycle arrest by suppressing p38/NF-κB signaling in human renal clear cell carcinoma

Objective: The anti-neoplastic effects of decitabine, an inhibitor of DNA promoter methylation, are beneficial for the treatment of renal cell carcinoma (RCC); however, the mechanism of action of decitabine is unclear. We analyzed gene expression profiling and identified specific pathways altered by...

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Pubblicato in:Int J Clin Exp Pathol
Autori principali: Shang, Donghao, Han, Tiandong, Xu, Xiuhong, Liu, Yuting
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637649/
https://ncbi.nlm.nih.gov/pubmed/26617834
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