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Down-regulation of TET2 in CD3(+) and CD34(+) cells of myelodysplastic syndromes and enhances CD34(+) cells proliferation

Aims and background: To investigate the expressions of TET2 mRNA in bone marrow CD3(+) and CD34(+) cells of the patients with myelodysplastic syndromes (MDS) and to study the effect of silencing TET2 by small interfering RNA (siRNA) on the biological characteristics of CD34(+) cells. Methods: CD3(+)...

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Dettagli Bibliografici
Pubblicato in:Int J Clin Exp Pathol
Autori principali: Zhang, Wei, Shao, Zonghong, Fu, Rong, Wang, Huaquan, Li, Lijuan, Liu, Hui
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637612/
https://ncbi.nlm.nih.gov/pubmed/26617797
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