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Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

Recently the cDNA encoding interleukin 13 (IL-13), a T-cell-derived cytokine, was cloned and expressed. The present study demonstrates that IL-13 induces IgG4 and IgE synthesis by human B cells. IL-13-induced IgG4 and IgE synthesis by unfractionated peripheral blood mononuclear cells and highly puri...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Punnonen, J, Aversa, G, Cocks, B G, McKenzie, A N, Menon, S, Zurawski, G, de Waal Malefyt, R, de Vries, J E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46375/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8097323/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.8.3730
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