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Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

Listeriosis in mice with the severe combined immunodeficiency (SCID) mutation is an established model in vivo and in vitro of interferon gamma (IFN-gamma)-dependent macrophage activation by natural killer (NK) cells during the development of natural immunity. We demonstrate that IFN-gamma production...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Tripp, C S, Wolf, S F, Unanue, E R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46374/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8097322/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.8.3725
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