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BTLA expression declines on B cells of the aged and is associated with low responsiveness to the trivalent influenza vaccine

Virus-neutralizing antibody and B cell responses to influenza A viruses were measured in 35 aged and 28 middle-aged individuals following vaccination with the 2012 and 2013 trivalent inactivated influenza vaccines. Antibody responses to the vaccine strains were lower in the aged. An analysis of B ce...

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Publicat a:Oncotarget
Autors principals: Kannan, Senthil, Kurupati, Raj K., Doyle, Susan A., Freeman, Gordon J., Schmader, Kenneth E., Ertl, Hildegund C.J.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637297/
https://ncbi.nlm.nih.gov/pubmed/26277622
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