High-fructose diet during periadolescent development increases depressive-like behavior and remodels the hypothalamic transcriptome in male rats

Fructose consumption, which promotes insulin resistance, hypertension, and dyslipidemia, has increased by over 25% since the 1970s. In addition to metabolic dysregulation, fructose ingestion stimulates the hypothalamic-pituitary-adrenal (HPA) axis leading to elevations in glucocorticoids. Adolescent...

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Veröffentlicht in:Psychoneuroendocrinology
Hauptverfasser: Harrell, Constance S., Burgado, Jillybeth, Kelly, Sean D., Johnson, Zachary P., Neigh, Gretchen N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637272/
https://ncbi.nlm.nih.gov/pubmed/26356038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2015.08.025
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