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Nifedipine Attenuation of Abdominal Aortic Aneurysm in Hypertensive and non-Hypertensive Mice: Mechanisms and Implications

Rupture of abdominal aortic aneurysm (AAA) is a lethal event. No oral medicine has been available to prevent or treat AAA. We have recently identified a novel mechanism of eNOS uncoupling by which AAA develops, in Angiotensin II (Ang II) infused hyperphenylalaninemia 1 (hph-1) mice. Using this uniqu...

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Détails bibliographiques
Publié dans:J Mol Cell Cardiol
Auteurs principaux: Miao, Xiao Niu, Siu, Kin Lung, Cai, Hua
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637219/
https://ncbi.nlm.nih.gov/pubmed/26254182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.07.031
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