Individuals with Primary Sclerosing Cholangitis have Elevated Levels of Biomarkers for Apoptosis but Not Necrosis

BACKGROUND AND AIM: Hepatocyte apoptosis or necrosis from accumulation of bile salts may play an important role in the disease progression of primary sclerosing cholangitis (PSC). The aim of the current study was to measure serum markers of hepatocyte apoptosis (cytokeratin 18 fragments - K18) and n...

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Veröffentlicht in:Dig Dis Sci
Hauptverfasser: Masuoka, Howard C., Vuppalanchi, Raj, Deppe, Ross, Bybee, Phelan, Comerford, Megan, Liangpunsakul, Suthat, Ghabril, Marwan, Chalasani, Naga
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637218/
https://ncbi.nlm.nih.gov/pubmed/26195313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-015-3805-7
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