hCLOCK Causes Rho-Kinase-Mediated Endothelial Dysfunction and NF-κB-Mediated Inflammatory Responses

Background. The human Circadian Locomotor Output Cycle protein Kaput (CLOCK) gene was originally discovered as a regulator of essential human daily rhythms. This seemingly innocuous gene was then found to be associated with a multitude of human malignancies, via several biochemical pathways. We aime...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Tang, Xiao, Guo, Daqiao, Lin, Changpo, Shi, Zhenyu, Qian, Ruizhe, Fu, Weiguo, Liu, Jianjun, Li, Xu, Fan, Longhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637096/
https://ncbi.nlm.nih.gov/pubmed/26583060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/671839
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