p21 deficiency is susceptible to osteoarthritis through STAT3 phosphorylation

INTRODUCTION: Osteoarthritis (OA) is a multifactorial disease, and recent studies have suggested that cell cycle–related proteins play a role in OA pathology. p21 was initially identified as a potent inhibitor of cell cycle progression. However, it has been proposed that p21 is a regulator of transc...

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Bibliografski detalji
Izdano u:Arthritis Res Ther
Glavni autori: Hayashi, Shinya, Fujishiro, Takaaki, Hashimoto, Shingo, Kanzaki, Noriyuki, Chinzei, Nobuaki, Kihara, Shinsuke, Takayama, Koji, Matsumoto, Tomoyuki, Nishida, Kotaro, Kurosaka, Masahiro, Kuroda, Ryosuke
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636813/
https://ncbi.nlm.nih.gov/pubmed/26546411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0828-6
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