Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells

BACKGROUND: Tip60 (KAT5) is the histone acetyltransferase (HAT) of the mammalian Tip60/NuA4 complex. While Tip60 is important for early mouse development and mouse embryonic stem cell (mESC) pluripotency, the function of Tip60 as reflected in a genome-wide context is not yet well understood. RESULTS...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Epigenetics Chromatin
Egile Nagusiak: Ravens, Sarina, Yu, Changwei, Ye, Tao, Stierle, Matthieu, Tora, Laszlo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2015
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636812/
https://ncbi.nlm.nih.gov/pubmed/26550034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-015-0039-z
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