Three-dimensional localization of polymer nanoparticles in cells using ToF-SIMS

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) three-dimensional (3D) depth profiling and a novel background subtraction method were used to localize polymeric nanoparticles within cells. Results showed that ToF-SIMS 3D depth profiling is capable of localizing polymer nanoparticles within...

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Udgivet i:Biointerphases
Main Authors: Graham, Daniel J., Wilson, John T., Lai, James J., Stayton, Patrick S., Castner, David G.
Format: Artigo
Sprog:Inglês
Udgivet: American Vacuum Society 2015
Fag:
In Focus: SIMS
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636497/
https://ncbi.nlm.nih.gov/pubmed/26531772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1116/1.4934795
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