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Reduced D2/D3 Receptor Binding of Extrastriatal and Striatal Regions in Temporal Lobe Epilepsy

OBJECTIVE: Dopamine is an endogenous neuromodulator in cortical circuits and the basal ganglia. In animal models of temporal lobe epilepsy (TLE), seizure threshold is modulated to some extent by dopamine, with D1-receptors having a pro- and D2-receptors an anticonvulsant effect. We aimed to extend o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bernedo Paredes, Viviane E., Buchholz, Hans-Georg, Gartenschläger, Martin, Breimhorst, Markus, Schreckenberger, Mathias, Werhahn, Konrad J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636381/
https://ncbi.nlm.nih.gov/pubmed/26544593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141098
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