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Nasal Levels of Antimicrobial Peptides in Allergic Asthma Patients and Healthy Controls: Differences and Effect of a Short 1,25(OH)(2) Vitamin D3 Treatment

BACKGROUND: Allergy is often accompanied by infections and lower levels of antimicrobial peptides (AMPs). Vitamin D has been shown to increase expression of selected AMPs. In this study we investigated whether antimicrobial peptide levels in nasal secretions of allergic asthma patients are lower tha...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Thijs, Willemien, Janssen, Kirsten, van Schadewijk, Annemarie M., Papapoulos, Socrates E., le Cessie, Saskia, Middeldorp, Saskia, Melissant, Christian F., Rabe, Klaus F., Hiemstra, Pieter S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636236/
https://ncbi.nlm.nih.gov/pubmed/26545199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140986
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