Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors

Human regulatory T cells (Tregs) are essential in maintaining immunological tolerance and suppress effector T cells. Tregs are commonly up-regulated in chronic infectious diseases such as tuberculosis (TB) and human immunodeficiency virus (HIV) infection and thereby hamper disease-specific immune re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lieske, Nora V., Tonby, Kristian, Kvale, Dag, Dyrhol-Riise, Anne M., Tasken, Kjetil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636186/
https://ncbi.nlm.nih.gov/pubmed/26544592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141903
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