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ROCK2 and MYLK variants under hypobaric hypoxic environment of high altitude associate with high altitude pulmonary edema and adaptation

OBJECTIVE: To date, a major class of kinases, serine–threonine kinase, has been scantly investigated in stress-induced rare, fatal (if not treated early), and morbid disorder, high altitude pulmonary edema (HAPE). This study examined three major serine–threonine kinases, ROCK2, MYLK, and JNK1, along...

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Detalhes bibliográficos
Publicado no:Appl Clin Genet
Main Authors: Pandey, Priyanka, Mohammad, Ghulam, Singh, Yogendra, Qadar Pasha, MA
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636093/
https://ncbi.nlm.nih.gov/pubmed/26586960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S90215
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