Rapid Memory T-cell Reconstitution Recapitulating CD45RA-depleted Haploidentical Transplant Graft Content in Patients with Hematologic Malignancies

T-cell depletion of an HLA-haploidentical graft is often used to prevent graft-vs.-host disease (GvHD), but the procedure may lead to increased graft failure, relapse, and infections due to delayed immune recovery. We hypothesized that selective depletion of the CD45RA+ subset can effectively reduce...

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Détails bibliographiques
Publié dans:Bone Marrow Transplant
Auteurs principaux: Triplett, Brandon M, Shook, David R, Eldridge, Paul, Li, Ying, Kang, Guolian, Dallas, Mari, Hartford, Christine, Srinivasan, Ashok, Chan, Wing Keung, Suwannasaen, Duangchan, Inaba, Hiroto, Pui, Ching-Hon, Leung, Wing
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636007/
https://ncbi.nlm.nih.gov/pubmed/25665048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2014.324
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