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Immunomodulation of the tumor microenvironment by neutralization of Semaphorin 4D

Semaphorin 4D is highly expressed at the invasive tumor margin and acts as a guidance molecule, restricting movement of tumoricidal immune cells into the tumor microenvironment. We recently showed that antibody neutralization of SEMA4D augmented activated monocyte and anticancer T-cell tumor penetra...

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Publicat a:Oncoimmunology
Autors principals: Evans, Elizabeth E, Paris, Mark, Smith, Ernest S, Zauderer, Maurice
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635900/
https://ncbi.nlm.nih.gov/pubmed/26587332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1054599
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