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The catalytic A1 domains of cholera toxin and heat-labile enterotoxin are potent DNA adjuvants that evoke mixed Th1/Th17 cellular immune responses

DNA encoded adjuvants are well known for increasing the magnitude of cellular and/or humoral immune responses directed against vaccine antigens. DNA adjuvants can also tune immune responses directed against vaccine antigens to better protect against infection of the target organism. Two potent DNA a...

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Bibliographic Details
Published in:Hum Vaccin Immunother
Main Authors: Bagley, Kenneth, Xu, Rong, Ota-Setlik, Ayuko, Egan, Michael, Schwartz, Jennifer, Fouts, Timothy
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635876/
https://ncbi.nlm.nih.gov/pubmed/26042527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1026498
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