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Tuberculosis vaccine development: Shifting focus amid increasing development challenges

A new tuberculosis vaccine is needed to replace or enhance BCG, which induces variable protection against Mycobacterium tuberculosis pulmonary infections in adults. Development of new TB vaccine candidates is severely hampered by the lack of a correlate of immunity, unproven animal models, and limit...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Graves, AJ, Hokey, DA
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635864/
https://ncbi.nlm.nih.gov/pubmed/26125249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1040955
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