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Keratoacanthoma of the Lip: Activation of the mTOR Pathway, Tumor Suppressor Proteins, and Tumor Senescence

The PI3K-PTEN-mTOR is one of the most important pathways involved in cancer development and progression; however, its role in keratoacanthoma (KA) is poorly understood. In this study, we investigated the activation of key proteins in the PI3K-mTOR pathway in lip KA. We analyzed the activation of the...

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Publicat a:Medicine (Baltimore)
Autors principals: Dillenburg, Caroline Siviero, Martins, Manoela Domingues, Meurer, Luise, Castilho, Rogerio Moraes, Squarize, Cristiane Helena
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer Health 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635754/
https://ncbi.nlm.nih.gov/pubmed/26402814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000001552
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