Codon-optimized filovirus DNA vaccines delivered by intramuscular electroporation protect cynomolgus macaques from lethal Ebola and Marburg virus challenges

Cynomolgus macaques were vaccinated by intramuscular electroporation with DNA plasmids expressing codon-optimized glycoprotein (GP) genes of Ebola virus (EBOV) or Marburg virus (MARV) or a combination of codon-optimized GP DNA vaccines for EBOV, MARV, Sudan virus and Ravn virus. When measured by ELI...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Vaccin Immunother
Main Authors: Grant-Klein, Rebecca J, Altamura, Louis A, Badger, Catherine V, Bounds, Callie E, Van Deusen, Nicole M, Kwilas, Steven A, Vu, Hong A, Warfield, Kelly L, Hooper, Jay W, Hannaman, Drew, Dupuy, Lesley C, Schmaljohn, Connie S
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635690/
https://ncbi.nlm.nih.gov/pubmed/25996997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1039757
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