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The epothilone B analogue ixabepilone in patients with advanced hepatobiliary cancers: a trial of the University of Chicago Phase II Consortium

PURPOSE: Hepatobiliary cancers respond poorly to cytotoxic chemotherapy. We evaluated the activity and safety of ixabepilone, an epothilone B analogue which stabilizes microtubules, in a phase II trial in patients with advanced cancers of the gallbladder, bile duct, and liver. METHODS: Eligible pati...

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Detalhes bibliográficos
Publicado no:Invest New Drugs
Main Authors: Nimeiri, Halla S., Singh, Deepti A., Kasza, Kristen, Taber, David A., Ansari, Rafat H., Vokes, Everett E., Kindler, Hedy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635688/
https://ncbi.nlm.nih.gov/pubmed/19669700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-009-9297-6
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