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Polyester: simulating RNA-seq datasets with differential transcript expression

Motivation: Statistical methods development for differential expression analysis of RNA sequencing (RNA-seq) requires software tools to assess accuracy and error rate control. Since true differential expression status is often unknown in experimental datasets, artificially constructed datasets must...

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Bibliografische gegevens
Gepubliceerd in:Bioinformatics
Hoofdauteurs: Frazee, Alyssa C., Jaffe, Andrew E., Langmead, Ben, Leek, Jeffrey T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635655/
https://ncbi.nlm.nih.gov/pubmed/25926345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv272
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