The membrane protein PrsS mimics σ(S) in protecting Staphylococcus aureus against cell wall-targeting antibiotics and DNA-damaging agents

Staphylococcus aureus possesses a lone extracytoplasmic function (ECF) sigma factor, σ(S). In Bacillus subtilis, the ECF sigma factor, σ(W), is activated through a proteolytic cascade that begins with cleavage of the RsiW anti-sigma factor by a site-1 protease (S1P), PrsW. We have identified a PrsW...

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Publicat a:Microbiology (Reading)
Autors principals: Krute, Christina N., Bell-Temin, Harris, Miller, Halie K., Rivera, Frances E., Weiss, Andy, Stevens, Stanley M., Shaw, Lindsey N.
Format: Artigo
Idioma:Inglês
Publicat: Society for General Microbiology 2015
Matèries:
Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635467/
https://ncbi.nlm.nih.gov/pubmed/25741016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.000065
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