Targeting extra-oral bitter taste receptors modulates gastrointestinal motility with effects on satiation

Bitter taste receptors (TAS2Rs) are present in extra-oral tissues, including gut endocrine cells. This study explored the presence and mechanism of action of TAS2R agonists on gut smooth muscle in vitro and investigated functional effects of intra-gastric administration of TAS2R agonists on gastric...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Avau, Bert, Rotondo, Alessandra, Thijs, Theo, Andrews, Christopher N., Janssen, Pieter, Tack, Jan, Depoortere, Inge
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635351/
https://ncbi.nlm.nih.gov/pubmed/26541810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15985
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