Blocking of fatty acid amide hydrolase activity with PF-04457845 in human brain: a positron emission tomography study with the novel radioligand [(11)C]CURB

Positron emission tomography with [(11)C]CURB was recently developed to quantify fatty acid amide hydrolase (FAAH), the enzyme responsible for hydrolyzing the endocannabinoid anandamide. This study investigated the test–retest reliability of [(11)C]CURB as well as its in vivo specificity and the val...

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Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Boileau, Isabelle, Rusjan, Pablo M, Williams, Belinda, Mansouri, Esmaeil, Mizrahi, Romina, De Luca, Vincenzo, Johnson, Douglas S, Wilson, Alan A, Houle, Sylvain, Kish, Stephen J, Tong, Junchao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635238/
https://ncbi.nlm.nih.gov/pubmed/26082009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.133
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