Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells

HIV reservoirs and production of viral antigens are not eliminated in chronically infected participants treated with combination antiretroviral therapy (cART). Novel therapeutic strategies aiming at viral reservoir elimination are needed to address chronic immune dysfunction and non-AIDS morbidities...

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Vydáno v:PLoS Pathog
Hlavní autoři: Sloan, Derek D., Lam, Chia-Ying Kao, Irrinki, Alivelu, Liu, Liqin, Tsai, Angela, Pace, Craig S., Kaur, Jasmine, Murry, Jeffrey P., Balakrishnan, Mini, Moore, Paul A., Johnson, Syd, Nordstrom, Jeffrey L., Cihlar, Tomas, Koenig, Scott
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634948/
https://ncbi.nlm.nih.gov/pubmed/26539983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005233
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