Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells

HIV reservoirs and production of viral antigens are not eliminated in chronically infected participants treated with combination antiretroviral therapy (cART). Novel therapeutic strategies aiming at viral reservoir elimination are needed to address chronic immune dysfunction and non-AIDS morbidities...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Sloan, Derek D., Lam, Chia-Ying Kao, Irrinki, Alivelu, Liu, Liqin, Tsai, Angela, Pace, Craig S., Kaur, Jasmine, Murry, Jeffrey P., Balakrishnan, Mini, Moore, Paul A., Johnson, Syd, Nordstrom, Jeffrey L., Cihlar, Tomas, Koenig, Scott
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634948/
https://ncbi.nlm.nih.gov/pubmed/26539983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005233
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