Dissecting Long-Term Glucose Metabolism Identifies New Susceptibility Period for Metabolic Dysfunction in Aged Mice

Metabolic disorders, like diabetes and obesity, are pathogenic outcomes of imbalance in glucose metabolism. Nutrient excess and mitochondrial imbalance are implicated in dysfunctional glucose metabolism with age. We used conplastic mouse strains with defined mitochondrial DNA (mtDNA) mutations on a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chauhan, Anuradha, Weiss, Heike, Koch, Franziska, Ibrahim, Saleh M., Vera, Julio, Wolkenhauer, Olaf, Tiedge, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634931/
https://ncbi.nlm.nih.gov/pubmed/26540285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140858
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