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A Euploid Line of Human Embryonic Stem Cells Derived from a 43,XX,dup(9q),+12,-14,-15,-18,-21 Embryo

Aneuploid embryos diagnosed by FISH-based preimplantation genetic screening (PGS) have been shown to yield euploid lines of human embryonic stem cells (hESCs) with a relatively high frequency. Given that the diagnostic procedure is usually based on the analysis of 1–2 blastomeres of 5 to 10-cell cle...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Fonseca, Simone Aparecida Siqueira, Costas, Roberta Montero, Morato-Marques, Mariana, Costa, Silvia, Alegretti, Jose Roberto, Rosenberg, Carla, da Motta, Eduardo Leme Alves, Serafini, Paulo C., Pereira, Lygia V.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634922/
https://ncbi.nlm.nih.gov/pubmed/26540511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140999
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