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Pleiotropic Effects of Immune Responses Explain Variation in the Prevalence of Fibroproliferative Diseases
Many diseases are differentially distributed among human populations. Differential selection on genetic variants in ancestral environments that coincidentally predispose to disease can be an underlying cause of these unequal prevalence patterns. Selected genes may be pleiotropic, affecting multiple...
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| Publicat a: | PLoS Genet |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4634921/ https://ncbi.nlm.nih.gov/pubmed/26540410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005568 |
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