Efficacy of Rituximab in Refractory Inflammatory Myopathies Associated with Anti- Synthetase Auto-Antibodies: An Open-Label, Phase II Trial

OBJECTIVE: Anti-synthetase syndrome (anti-SS) is frequently associated with myositis and interstitial lung disease (ILD). We evaluated prospectively, in a multicenter, open-label, phase II study, the efficacy of rituximab on muscle and lung outcomes. METHODS: Patients were enrolled if they were refr...

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Publicat a:PLoS One
Autors principals: Allenbach, Yves, Guiguet, Marguerite, Rigolet, Aude, Marie, Isabelle, Hachulla, Eric, Drouot, Laurent, Jouen, Fabienne, Jacquot, Serge, Mariampillai, Kuberaka, Musset, Lucile, Grenier, Philippe, Devilliers, Herve, Hij, Adrian, Boyer, Olivier, Herson, Serge, Benveniste, Olivier
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634756/
https://ncbi.nlm.nih.gov/pubmed/26539981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133702
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