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Membrane stiffening by STOML3 facilitates mechanosensation in sensory neurons
Sensing force is crucial to maintain the viability of all living cells. Despite its fundamental importance, how force is sensed at the molecular level remains largely unknown. Here we show that stomatin-like protein-3 (STOML3) controls membrane mechanics by binding cholesterol and thus facilitates f...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Pub. Group
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4633829/ https://ncbi.nlm.nih.gov/pubmed/26443885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9512 |
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