IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma

The recent identification of IDH mutations in gliomas and several other cancers suggests that this pathway is involved in oncogenesis; however effector functions are complex and yet incompletely understood. To study the regulatory effects of IDH on hypoxia-inducible-factor 1-alpha (HIF1A), a driving...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kickingereder, Philipp, Sahm, Felix, Radbruch, Alexander, Wick, Wolfgang, Heiland, Sabine, Deimling, Andreas von, Bendszus, Martin, Wiestler, Benedikt
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633672/
https://ncbi.nlm.nih.gov/pubmed/26538165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16238
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares