Ape parasite origins of human malaria virulence genes

Antigens encoded by the var gene family are major virulence factors of the human malaria parasite Plasmodium falciparum, exhibiting enormous intra- and interstrain diversity. Here we use network analysis to show that var architecture and mosaicism are conserved at multiple levels across the Laverani...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Larremore, Daniel B., Sundararaman, Sesh A., Liu, Weimin, Proto, William R., Clauset, Aaron, Loy, Dorothy E., Speede, Sheri, Plenderleith, Lindsey J., Sharp, Paul M., Hahn, Beatrice H., Rayner, Julian C., Buckee, Caroline O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633637/
https://ncbi.nlm.nih.gov/pubmed/26456841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9368
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