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Site-specific labeling of proteins for electron microscopy

Electron microscopy is commonly employed to determine the subunit organization of large macromolecular assemblies. However, the field lacks a robust molecular labeling methodology for unambiguous identification of constituent subunits. We present a strategy that exploits the unique properties of an...

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Detalles Bibliográficos
Publicado en:J Struct Biol
Main Authors: Dambacher, Corey M., Lander, Gabriel C.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633364/
https://ncbi.nlm.nih.gov/pubmed/26409249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2015.09.010
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